Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569191 | 0.88 | TOP1 (0.46) | TOP1CYP3A4CYP2C9 | |
| SCHEMBL9509563 | 0.81 | TOP1 (0.40) | TOP1 | |
| SCHEMBL9509713 | 0.76 | TOP1 (0.40) | TOP1 | |
| SCHEMBL9560540 | 0.74 | TOP1 (0.36) | TOP1CYP3A4 | |
| SCHEMBL9560364 | 0.73 | TOP1 (0.38) | TOP1 | |
| SCHEMBL9569195 | 0.73 | TOP1 (0.40) | TOP1 | |
| SCHEMBL9560596 | 0.71 | KDM4E (0.38) | TOP1 | |
| SCHEMBL9510131 | 0.70 | TOP1 (0.36) | TOP1 | |
| SCHEMBL9560451 | 0.69 | STAT3 (0.36) | TOP1 | |
| SCHEMBL9509558 | 0.68 | TOP1 (0.52) | TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |