Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983036 | 0.79 | LMNA (0.47) | LMNA | |
| SCHEMBL5982461 | 0.75 | GLA (0.43) | LMNA | |
| SCHEMBL5983070 | 0.74 | HPGD (0.45) | LMNAHTR7 | |
| SCHEMBL5982410 | 0.74 | HPGD (0.45) | LMNAHTR7 | |
| SCHEMBL5982386 | 0.74 | HPGD (0.45) | LMNAHTR7 | |
| SCHEMBL5983095 | 0.71 | SMN1; SMN2 (0.45) | LMNA | |
| SCHEMBL5982521 | 0.70 | ATM (0.36) | LMNAHTR7 | |
| SCHEMBL5981623 | 0.68 | TBXAS1 (0.31) | — | |
| SCHEMBL5982130 | 0.68 | TBXAS1 (0.45) | LMNA | |
| SCHEMBL5981832 | 0.67 | KEAP1 (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560330-A2 | Substituted benzimidazolyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-09-15 | — | — | EP | disclosed |