Sulfuric Acid

Sulfuric Acid

SCHEMBL9569298

CCc1cc(NC(C)NS(C)(=O)=O)ccc1N.O=S(=O)(O)O

nearest known ligand 0.34

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C known ✓ P18825 1/20 0.32
ADRA1A known ✓ P35348 1/20 0.32
ADRA1B known ✓ P35368 1/20 0.32
ADRB2 known ✓ P07550 1/20 0.30
ADRB1 known ✓ P08588 1/20 0.30
ADRB3 known ✓ P13945 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
POLB P06746 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
FFAR4 Q5NUL3 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KDM4E B2RXH2 2/20 0.30
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10336737 0.96 ALDH1A1 (0.35) CTDSP1ALDH1A1MAPTPOLBCA1
Sulfuric Acid SCHEMBL10429917 0.83 ALDH1A1 (0.42) CTDSP1ALDH1A1MAPTPOLBCA1
Sulfuric Acid SCHEMBL11036141 0.83 CTDSP1 (0.37) CTDSP1ALDH1A1MAPTPOLBCA1
Sulfuric Acid SCHEMBL11785191 0.82 ALDH1A1 (0.41) CTDSP1ALDH1A1MAPTPOLBCA1
SCHEMBL8633217 0.79 ALDH1A1 (0.41) ALDH1A1MAPTCA1CA2CA12
Sulfuric Acid SCHEMBL11087468 0.78 ALDH1A1 (0.38) ALDH1A1MAPTPOLBCA1CA2
Sulfuric Acid SCHEMBL9569292 0.74 MAPT (0.39) CTDSP1ALDH1A1MAPTPOLBADRA2C
Sulfuric Acid SCHEMBL8632857 0.73 HRH4 (0.32) ALDH1A1MAPTPOLBLMNA
SCHEMBL9289658 0.73 ALDH1A1 (0.38) ALDH1A1MAPTCA1CA2CA12
Sulfuric Acid SCHEMBL10792543 0.71 ALDH1A1 (0.40) CTDSP1ALDH1A1MAPTPOLBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0546711-A1 Method for forming dye images KONICA CORPORATION (JP) 1993-06-16 EP disclosed