Sulfuric Acid

Sulfuric Acid

SCHEMBL8632857

CCc1cc(N(CC)C(C)NS(C)(=O)=O)ccc1N.O=S(=O)(O)O

nearest known ligand 0.32

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 4/20 0.32
NR3C2 P08235 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
IGLV6-57 P01721 1/20 0.31
POLB P06746 1/20 0.31
S100B P04271 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL6545764 0.88 S100B (0.46) HRH4NR3C2ALDH1A1MAPTLMNA
Sulfuric Acid SCHEMBL10702698 0.86 S100B (0.44) HRH4NR3C2ALDH1A1MAPTLMNA
Sulfuric Acid SCHEMBL5157371 0.86 S100B (0.44) HRH4NR3C2ALDH1A1MAPTLMNA
SCHEMBL793227 0.83 S100B (0.49) HRH4NR3C2ALDH1A1MAPTLMNA
SCHEMBL9847596 0.83 S100B (0.49) HRH4NR3C2ALDH1A1MAPTLMNA
Sulfuric Acid SCHEMBL8960974 0.83 ALDH1A1 (0.39) NR3C2ALDH1A1MAPTLMNAHTT
Water SCHEMBL9591233 0.82 S100B (0.48) HRH4NR3C2ALDH1A1MAPTLMNA
Hydrochloric Acid SCHEMBL9188528 0.82 S100B (0.48) HRH4NR3C2ALDH1A1MAPTLMNA
Sulfurous Acid SCHEMBL10660633 0.81 S100B (0.43) NR3C2ALDH1A1MAPTLMNAHTT
SCHEMBL8766774 0.81 S100B (0.43) HRH4NR3C2ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510898-B1 Silver halide color photographic light sensitive material KONISHIROKU PHOTO IND (JP) 1998-07-01 EP disclosed
EP-0422505-A1 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1991-04-17 EP disclosed
EP-0296780-A2 Light-sensitive silver halide color photographic material containing novel cyan coupler KONICA CORPORATION (JP) 1988-12-28 EP disclosed