Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | PI4KA | P42356 | 2/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | AHCY | P23526 | 5/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | POLG | P54098 | 1/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569602 | 0.86 | ENPP1 (0.55) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL13648201 | 0.76 | ENPP1 (0.65) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL8709070 | 0.75 | FAP (0.56) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9569474 | 0.75 | ENPP1 (0.53) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9569496 | 0.75 | ENPP1 (0.53) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9885880 | 0.74 | ADORA2A (0.69) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9569502 | 0.73 | CYP3A4 (0.48) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9569477 | 0.73 | CYP3A4 (0.48) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9569488 | 0.73 | CYP3A4 (0.48) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL3302566 | 0.73 | FGFR1 (0.71) | ENPP1ADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |