Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.50 |
| ▸ | CA1 | P00915 | 9/20 | 0.50 |
| ▸ | CA9 | Q16790 | 7/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796612 | 0.81 | TTR (0.47) | CDK2MAOAMAOBFTOKCNA3 | |
| SCHEMBL1501133 | 0.81 | MAOA (0.47) | MAOAMAOBFTOCYP2C9MAPK1 | |
| Hydrochloric Acid SCHEMBL27577221 | 0.79 | TTR (0.46) | CDK2MAOAMAOBFTOKCNA3 | |
| SCHEMBL3799272 | 0.77 | MAOA (0.39) | CA2CA1CA9MAOAMAOB | |
| SCHEMBL2087127 | 0.74 | CA2 (0.51) | CA2CA1CA9CDK2MAOA | |
| SCHEMBL9138970 | 0.74 | CDK2 (0.78) | CA2CA1CA9CDK2FTO | |
| SCHEMBL8799961 | 0.72 | MAOB (0.46) | CA2CA1MAOAMAOBFTO | |
| SCHEMBL1037129 | 0.69 | CA2 (0.50) | CA2CA1CA9CDK2CA12 | |
| SCHEMBL4907475 | 0.69 | CA1 (0.55) | CA2CA1CA9CDK2MAOA | |
| SCHEMBL275378 | 0.69 | MAOA (0.45) | CA2CA1CA9CDK2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560554-A2 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5169860-A | Benzofuran or benzothiophene arylsulfonylureas | ELI LILLY AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |