Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569845 | 0.83 | NPC1 (0.33) | ICMTNPC1GAARAB9ASMN1; SMN2 | |
| SCHEMBL9569896 | 0.72 | SSTR4 (0.33) | NPC1GAARAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL6000951 | 0.69 | LTA4H (0.41) | RAB9A | |
| SCHEMBL9569843 | 0.68 | GAA (0.36) | NPC1GAARAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9569850 | 0.68 | DRD4 (0.35) | CCR6KCNH2DRD4SSTR4 | |
| SCHEMBL6468423 | 0.68 | LTA4H (0.39) | RAB9A | |
| Fluoride SCHEMBL28371495 | 0.67 | KIF11 (0.46) | RAB9ASMN1; SMN2CCR6KCNH2 | |
| SCHEMBL23825152 | 0.66 | LTA4H (0.38) | CCR6KCNH2 | |
| SCHEMBL821312 | 0.66 | CA4 (0.40) | CCR6KCNH2 | |
| SCHEMBL13039942 | 0.66 | CA4 (0.40) | CCR6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227500-A | Halogenated 1,3-dioxolanes and derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0529741-A1 | Procedure for the preparation of halogenated 1,3-dioxolanes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |
| US-5057586-A | Fluoropolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-15 | — | — | US | disclosed |
| US-4973714-A | ADDITION POLYMERS, FLUOROPOLYMERS, HEAT RESISTANCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-11-27 | — | — | US | disclosed |
| US-4810806-A | FROM A HALOETHYL CARBOXYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0301881-A1 | Halogenated 1,3-dioxolanes and derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-01 | — | — | EP | disclosed |