Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344521 | 0.72 | KCNH2 (0.32) | GAANPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL440309 | 0.71 | CA4 (0.37) | GAAHSD17B10TSHRLTA4HDRD2 | |
| SCHEMBL9569845 | 0.69 | NPC1 (0.33) | GAANPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL17593734 | 0.68 | DRD2 (0.35) | PDK2DRD2HTR1AADRA1D | |
| SCHEMBL9569900 | 0.68 | ICMT (0.32) | GAANPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL29839565 | 0.65 | POLB (0.37) | GAANPC1TSHRLTA4HDRD2 | |
| SCHEMBL28534409 | 0.65 | LTA4H (0.33) | GAATSHRLTA4HNPSR1CA4 | |
| SCHEMBL7657866 | 0.64 | SSTR4 (0.35) | TSHRLTA4HDRD2ALDH1A1CA4 | |
| SCHEMBL10594921 | 0.64 | GAA (0.38) | GAATSHRNPSR1HTR1AADRA1D | |
| SCHEMBL6321287 | 0.64 | POLB (0.39) | GAANPC1HSD17B10TSHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227500-A | Halogenated 1,3-dioxolanes and derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0529741-A1 | Procedure for the preparation of halogenated 1,3-dioxolanes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |
| US-5057586-A | Fluoropolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-15 | — | — | US | disclosed |
| US-4973714-A | ADDITION POLYMERS, FLUOROPOLYMERS, HEAT RESISTANCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-11-27 | — | — | US | disclosed |
| US-4810806-A | FROM A HALOETHYL CARBOXYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0301881-A1 | Halogenated 1,3-dioxolanes and derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-01 | — | — | EP | disclosed |