Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598053 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNATHRBTSHRMAPK1 | |
| SCHEMBL14416109 | 0.79 | HRH4 (0.39) | TSHR | |
| SCHEMBL18506826 | 0.78 | — | — | |
| SCHEMBL1461161 | 0.78 | HSD11B1 (0.41) | ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL889016 | 0.76 | — | — | |
| SCHEMBL27220869 | 0.75 | TBXAS1 (0.31) | — | |
| SCHEMBL27220867 | 0.75 | HRH4 (0.33) | — | |
| SCHEMBL27839146 | 0.75 | TLR7 (0.45) | ALDH1A1 | |
| SCHEMBL10794430 | 0.74 | TBXAS1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL859443 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |