Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.71 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.62 |
| ▸ | MPO | P05164 | 3/20 | 0.47 |
| ▸ | XDH | P47989 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8869860 | 0.99 | SIGMAR1 (0.69) | SIGMAR1TMEM97MPOXDHHTR1A | |
| SCHEMBL10802670 | 0.92 | SIGMAR1 (0.63) | SIGMAR1TMEM97HTR1AHTR7NPY5R | |
| SCHEMBL15295194 | 0.85 | TMEM97 (0.66) | SIGMAR1TMEM97HTR1AHTR7NPY5R | |
| SCHEMBL8870033 | 0.83 | TMEM97 (0.67) | SIGMAR1TMEM97HTR1AHTR7CNR2 | |
| SCHEMBL11204469 | 0.83 | SIGMAR1 (0.52) | SIGMAR1TMEM97MPOXDHHTR1A | |
| SCHEMBL8870438 | 0.82 | TMEM97 (0.66) | SIGMAR1TMEM97HTR1AHTR7CNR2 | |
| SCHEMBL15292530 | 0.81 | TMEM97 (0.62) | SIGMAR1TMEM97HTR1AHTR7NPY5R | |
| SCHEMBL9570355 | 0.81 | TMEM97 (0.62) | SIGMAR1TMEM97HTR1AHTR7NPY5R | |
| SCHEMBL7282589 | 0.81 | SIGMAR1 (0.58) | SIGMAR1TMEM97TP53ADRA2AMAPT | |
| SCHEMBL8902235 | 0.81 | NPY5R (0.56) | SIGMAR1TMEM97NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572308-A2 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-12-01 | — | — | EP | disclosed |