Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL8869500 | 0.99 | TMEM97 (0.60) | TMEM97SIGMAR1HTR1AHTR7CNR2 | |
| SCHEMBL15295194 | 0.85 | TMEM97 (0.66) | TMEM97SIGMAR1HTR1AHTR7CNR2 | |
| SCHEMBL8870033 | 0.83 | TMEM97 (0.67) | TMEM97SIGMAR1HTR1AHTR7CNR2 | |
| SCHEMBL8870438 | 0.82 | TMEM97 (0.66) | TMEM97SIGMAR1HTR1AHTR7CNR2 | |
| SCHEMBL9570335 | 0.81 | SIGMAR1 (0.71) | TMEM97SIGMAR1HTR1AHTR7CNR2 | |
| SCHEMBL15292530 | 0.81 | TMEM97 (0.62) | TMEM97SIGMAR1HTR1AHTR7CNR2 | |
| Hydrochloric Acid SCHEMBL8869860 | 0.80 | SIGMAR1 (0.69) | TMEM97SIGMAR1HTR1AHTR7NPY5R | |
| SCHEMBL15283315 | 0.80 | TMEM97 (0.63) | TMEM97SIGMAR1HTR1AHTR7CNR2 | |
| SCHEMBL30214703 | 0.78 | TMEM97 (0.60) | TMEM97SIGMAR1NPY5RDRD2DRD4 | |
| SCHEMBL16932349 | 0.78 | TMEM97 (0.60) | TMEM97SIGMAR1NPY5RDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572308-A2 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-12-01 | — | — | EP | disclosed |