Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597742 | 0.79 | KMT2A (0.30) | — | |
| SCHEMBL15221588 | 0.79 | HRH4 (0.47) | — | |
| Iodide SCHEMBL632376 | 0.79 | NOS3 (0.37) | PDE10A | |
| SCHEMBL2093661 | 0.78 | — | — | |
| SCHEMBL3632656 | 0.78 | NOS2 (0.42) | — | |
| SCHEMBL5561625 | 0.75 | KCNH2 (0.48) | — | |
| Iodide SCHEMBL78512 | 0.73 | KCNH2 (0.47) | — | |
| SCHEMBL5536928 | 0.72 | TBXAS1 (0.44) | — | |
| SCHEMBL5538219 | 0.72 | TBXAS1 (0.44) | — | |
| SCHEMBL5531368 | 0.72 | TBXAS1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |