Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570151 | 0.79 | AGTR1 (0.36) | KDM4EMAPTTSHRHPGD | |
| SCHEMBL9570306 | 0.78 | AGTR1 (0.39) | KDM4EMAPTALDH1A1 | |
| SCHEMBL22522129 | 0.74 | HRH3 (0.45) | KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL16638735 | 0.69 | KDM4E (0.36) | KDM4ETSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL23712947 | 0.67 | KDM4E (0.35) | KDM4ETSHRALDH1A1HPGD | |
| SCHEMBL23712823 | 0.67 | KDM4E (0.35) | KDM4ETSHRALDH1A1HPGD | |
| SCHEMBL25383117 | 0.67 | AGTR1 (0.44) | KDM4EMAPTTSHR | |
| SCHEMBL11923712 | 0.65 | AGTR1 (0.43) | KDM4E | |
| SCHEMBL10252360 | 0.65 | KDM4E (0.36) | KDM4ETSHRALDH1A1HPGD | |
| SCHEMBL9570106 | 0.64 | AGTR1 (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |