Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1511313 | 0.88 | CYP4F2 (0.69) | CYP4F2CYP4A11TAAR1ALDH1A1GAA | |
| SCHEMBL12602245 | 0.85 | CYP4F2 (0.56) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12098456 | 0.85 | CYP4F2 (0.45) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL956095 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11TAAR1ALDH1A1GAA | |
| SCHEMBL956957 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11TAAR1ALDH1A1GAA | |
| SCHEMBL9157019 | 0.82 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28641430 | 0.82 | EGFR (0.43) | CYP4F2CYP4A11ALDH1A1GAAKMT2A | |
| SCHEMBL28873178 | 0.81 | CYP4F2 (0.52) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL14935427 | 0.81 | IAPP (0.59) | CYP4F2CYP4A11TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31248156 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009429-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF CXCR2 | NOVARTIS AG (CH) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009429-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF CXCR2 | CXCR2, CXCR1, CXCR3 | CYP4F2 1678/4885CYP4A11 1251/4885TAAR1 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.