Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687145 | 0.88 | CYP4F2 (0.67) | CYP4F2CYP4A11KMT2AMEN1ALDH1A1 | |
| SCHEMBL30753435 | 0.88 | LMNA (0.48) | CYP4F2CYP4A11KMT2AMEN1ALDH1A1 | |
| SCHEMBL21715380 | 0.88 | LMNA (0.48) | CYP4F2CYP4A11KMT2AMEN1ALDH1A1 | |
| SCHEMBL29014549 | 0.85 | TSHR (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3941285 | 0.85 | HPGD (0.50) | KMT2AMEN1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL12602245 | 0.84 | CYP4F2 (0.56) | CYP4F2CYP4A11KMT2AMEN1ALDH1A1 | |
| SCHEMBL7331644 | 0.83 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL30800373 | 0.83 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL21715451 | 0.82 | CYP4F2 (0.41) | CYP4F2CYP4A11KMT2AMEN1ALDH1A1 | |
| SCHEMBL30753448 | 0.82 | CYP4F2 (0.41) | CYP4F2CYP4A11KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177780-B | Pyrimidine compounds containing acidic groups | 阿普罗斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |