Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394814 | 0.88 | CYP4F2 (0.69) | CYP4F2CYP4A11MAPTALDH1A1NLRP3 | |
| SCHEMBL12602245 | 0.85 | CYP4F2 (0.56) | CYP4F2CYP4A11ALDH1A1NLRP3HTT | |
| SCHEMBL10955526 | 0.85 | ALDH1A1 (0.48) | CYP4F2CYP4A11MAPTALDH1A1NLRP3 | |
| SCHEMBL3951620 | 0.83 | PLAAT3 (0.51) | MAPTALDH1A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL957050 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11MAPTALDH1A1NLRP3 | |
| SCHEMBL956957 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11MAPTALDH1A1NLRP3 | |
| SCHEMBL28873178 | 0.81 | CYP4F2 (0.52) | CYP4F2CYP4A11ALDH1A1POLB | |
| SCHEMBL7323440 | 0.79 | PLAAT3 (0.49) | CYP4F2CYP4A11MAPTALDH1A1HPGD | |
| SCHEMBL7331092 | 0.79 | TAAR1 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL717900 | 0.78 | TDP1 (0.56) | CYP4F2CYP4A11MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009429-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF CXCR2 | NOVARTIS AG (CH) | 2011-01-13 | — | — | US | disclosed |
| US-4042596-A | 2-Alkyl-5-phenethyl-4-oxazolecarboxylic acids and derivatives | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | disclosed |
| US-3994915-A | Preparation of substituted oxazoles | SANDOZ, INC. (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009429-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF CXCR2 | CXCR2, CXCR1, CXCR3 | CYP4F2 1678/4885CYP4A11 1251/4885MAPT 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.