SCHEMBL9570910

SCHEMBL9570910

Cc1cccc(C(COCc2ccc(F)c(Oc3ccccc3)c2)C(F)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.37
TACR1 P25103 15/20 0.37
NPSR1 Q6W5P4 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
CACNA1F O60840 1/20 0.35
CACNA1D Q01668 1/20 0.35
CACNA1S Q13698 1/20 0.35
CACNA1C Q13936 1/20 0.35
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSS P25774 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570679 0.90 FFAR1 (0.47) FFAR1TACR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570885 0.89 TACR1 (0.37) FFAR1TACR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570693 0.89 TACR1 (0.36) FFAR1TACR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570703 0.88 TACR1 (0.44) FFAR1TACR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570739 0.88 FFAR1 (0.34) FFAR1TACR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570748 0.88 TACR1 (0.42) FFAR1TACR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570666 0.87 TACR1 (0.35) FFAR1TACR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570571 0.86 CETP (0.43) FFAR1TACR1NPSR1L3MBTL1GAA
SCHEMBL9561249 0.85 FFAR1 (0.40) FFAR1TACR1L3MBTL1
SCHEMBL9570632 0.85 DUT (0.35) FFAR1TACR1CACNA1FCACNA1DCACNA1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed