SCHEMBL9570693

SCHEMBL9570693

Cc1ccc(C(COCc2ccc(F)c(Oc3ccccc3)c2)C(F)(F)F)cc1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 10/20 0.36
FFAR1 O14842 2/20 0.35
CACNA1F O60840 1/20 0.34
CACNA1D Q01668 1/20 0.34
CACNA1S Q13698 1/20 0.34
CACNA1C Q13936 1/20 0.34
DUT P33316 1/20 0.33
TTR P02766 1/20 0.33
LMNA P02545 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570771 0.91 FFAR1 (0.35) TACR1FFAR1CACNA1FCACNA1DCACNA1S
SCHEMBL9561249 0.91 FFAR1 (0.40) TACR1FFAR1TTRLPAR1LPAR5
SCHEMBL9570632 0.91 DUT (0.35) TACR1FFAR1CACNA1FCACNA1DCACNA1S
SCHEMBL9560935 0.91 LTA4H (0.36) TACR1FFAR1CACNA1FCACNA1DCACNA1S
SCHEMBL9561512 0.90 TACR1 (0.36) TACR1FFAR1CACNA1FCACNA1DCACNA1S
SCHEMBL409992 0.89 LTA4H (0.41) FFAR1CACNA1CLMNA
SCHEMBL9560897 0.89 FFAR1 (0.37) TACR1FFAR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570611 0.89 MEN1 (0.37) TACR1FFAR1CACNA1FCACNA1DCACNA1S
SCHEMBL9570910 0.89 FFAR1 (0.37) TACR1FFAR1CACNA1FCACNA1DCACNA1S
SCHEMBL9561242 0.89 CETP (0.34) TACR1FFAR1CACNA1FCACNA1DCACNA1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed