SCHEMBL9570732

SCHEMBL9570732

Fc1ccc(C(COCc2cccc(Oc3ccccc3)n2)C(F)(F)F)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LOXL2 Q9Y4K0 2/20 0.35
KCNH2 Q12809 1/20 0.35
PPARG P37231 1/20 0.33
POLB P06746 1/20 0.32
ATM Q13315 1/20 0.32
LOX P28300 1/20 0.32
F2 P00734 3/20 0.32
F10 P00742 3/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
ST14 Q9Y5Y6 1/20 0.32
HSD17B14 Q9BPX1 1/20 0.31
LTA4H P09960 1/20 0.31
EPHX2 P34913 1/20 0.31
EGLN2 Q96KS0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560496 0.90 CETP (0.36) KCNH2LTA4HEPHX2
SCHEMBL9570714 0.89 KCNH2 (0.33) LOXL2KCNH2LOXF2F10
SCHEMBL9560885 0.88 LTA4H (0.42) MEN1KMT2AL3MBTL1KCNH2POLB
SCHEMBL10622866 0.80 KCNH2 (0.39) L3MBTL1LOXL2KCNH2LOXF2
SCHEMBL9570765 0.78 CETP (0.44) LTA4HEPHX2
SCHEMBL27690318 0.75 KCNH2 (0.53) MEN1KMT2AHTTL3MBTL1LOXL2
SCHEMBL9570609 0.75 RAB9A (0.30)
SCHEMBL9570770 0.75 SLC6A2 (0.36) MEN1KMT2AKCNH2SCN9A
SCHEMBL10360899 0.74 MEN1 (0.39) MEN1KMT2AHTTL3MBTL1LOXL2
SCHEMBL10360868 0.74 MEN1 (0.38) MEN1KMT2AHTTL3MBTL1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed