Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.53 |
| ▸ | HTR3A | P46098 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8985215 | 0.94 | ADRA2A (0.48) | ADRA2AADRA2BHTR3AADRA2CSLC6A4 | |
| Fumaric Acid SCHEMBL8985218 | 0.94 | ADRA2A (0.48) | ADRA2AADRA2BHTR3AADRA2CSLC6A4 | |
| SCHEMBL27249969 | 0.77 | NPSR1 (0.59) | ADRA2AADRA2BHTR3AADRA2CSLC6A4 | |
| SCHEMBL27249980 | 0.70 | HTR3A (0.53) | ADRA2AADRA2BHTR3AADRA2CSLC6A4 | |
| SCHEMBL8985190 | 0.70 | NOTUM (0.36) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL9260935 | 0.69 | HTR3A (0.43) | ADRA2AADRA2BHTR3AADRA2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL8985242 | 0.69 | NOTUM (0.35) | ALDH1A1KMT2AMEN1 | |
| Ramosetron SCHEMBL13531398 | 0.69 | HTR3A (0.84) | ADRA2AADRA2BHTR3AADRA2CSLC6A4 | |
| Ramosetron SCHEMBL9048395 | 0.69 | HTR3A (0.84) | ADRA2AADRA2BHTR3AADRA2CSLC6A4 | |
| Ramosetron SCHEMBL16701 | 0.69 | HTR3A (0.84) | ADRA2AADRA2BHTR3AADRA2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532754-A1 | TETRAHYDROIMIDAZOPYRIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-24 | — | — | EP | claimed |