SCHEMBL9570815

SCHEMBL9570815

COc1ccc(C(COCc2ccc(F)c(Oc3ccccc3)c2)C(F)(F)F)cc1OC

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.44
ALDH1A1 P00352 2/20 0.41
FFAR1 O14842 1/20 0.37
ABCB1 P08183 3/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
HTT P42858 2/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPT P10636 2/20 0.34
ADRB2 P07550 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9561249 0.91 FFAR1 (0.40) TTRALDH1A1FFAR1HTT
SCHEMBL9570679 0.89 FFAR1 (0.47) TTRFFAR1
SCHEMBL9570666 0.88 TACR1 (0.35) TTRFFAR1
SCHEMBL9570739 0.87 FFAR1 (0.34) TTRFFAR1
SCHEMBL9570693 0.86 TACR1 (0.36) TTRFFAR1LMNA
SCHEMBL9570771 0.86 FFAR1 (0.35) TTRALDH1A1FFAR1
SCHEMBL9570632 0.86 DUT (0.35) TTRFFAR1
SCHEMBL9560935 0.86 LTA4H (0.36) FFAR1
SCHEMBL9561512 0.85 TACR1 (0.36) TTRALDH1A1FFAR1HTTPPARG
SCHEMBL409992 0.84 LTA4H (0.41) FFAR1LMNAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed