Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862583 | 0.84 | ESR1 (0.44) | ESR1ESR2PDE2A | |
| SCHEMBL9570660 | 0.84 | ESR1 (0.44) | ESR1ESR2PDE2A | |
| SCHEMBL13965561 | 0.82 | GRIA4 (0.41) | LMNAESR1ESR2TYRSMN1; SMN2 | |
| SCHEMBL9570892 | 0.81 | ESR1 (0.42) | ESR1ESR2PDE2A | |
| SCHEMBL9570735 | 0.80 | ESR1 (0.44) | ESR1ESR2AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL9570823 | 0.80 | ESR1 (0.44) | ESR1ESR2TYRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9570647 | 0.78 | ESR1 (0.40) | ESR1ESR2PDE2A | |
| SCHEMBL9570698 | 0.78 | ESR1 (0.46) | ESR1ESR2AOC3 | |
| SCHEMBL9570755 | 0.77 | ABCB11 (0.46) | ESR1ESR2TSHRAOC3ALDH1A1 | |
| SCHEMBL9570673 | 0.77 | ESR1 (0.50) | LMNAESR1ESR2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545891-A2 | Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4840971-A | INSECTICIDES, MITICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0240978-A2 | Ether compounds, process for their preparation, compositions containing the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-14 | — | — | EP | disclosed |