Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242790 | 0.85 | — | — | |
| SCHEMBL910129 | 0.83 | CYP1A2 (0.35) | ALDH1A1 | |
| SCHEMBL3185584 | 0.71 | CYP3A4 (0.41) | CA1CA2CA9CYP3A4CA7 | |
| SCHEMBL1343169 | 0.71 | DYRK1A (0.42) | ALDH1A1CYP3A4GAADYRK1AMAPK1 | |
| SCHEMBL22288144 | 0.71 | ALDH1A1 (0.33) | CA1CA2ALDH1A1CA9CA12 | |
| SCHEMBL18245345 | 0.71 | ALDH1A1 (0.33) | ALDH1A1AHRMAPK1 | |
| SCHEMBL94460 | 0.70 | GAA (0.33) | CA1CA2CA4CA6GAA | |
| SCHEMBL9819737 | 0.69 | ALDH1A1 (0.44) | CA1CA2ALDH1A1CA9CYP3A4 | |
| SCHEMBL95291 | 0.69 | — | — | |
| SCHEMBL8098752 | 0.67 | JAK2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826802-B1 | METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION | ZEON CORP (JP) | 2021-03-10 | — | — | EP | disclosed |
| US-20180127520-A1 | METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION | ZEON CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
| US-9850325-B2 | Method for producing ring-opening metathesis polymer hydride, and resin composition | ZEON CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20150051353-A1 | METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION | ZEON CORPORATION (JP) | 2015-02-19 | — | — | US | disclosed |
| EP-2826802-A1 | METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION | Zeon Corporation (JP) | 2015-01-21 | — | — | EP | disclosed |
| EP-0547690-A1 | Use of 17B-acyl-4-aza-5alpha-androst-1-en-3-ones for the preparation of a medicament for the prevention of prostatic carcinoma | MERCK & CO. INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| US-5151429-A | Enzyme inhibitors, skin disorders and antiandrogens | MERCK & CO., INC. (US) | 1992-09-29 | — | — | US | disclosed |
| US-5138063-A | Testosterone reductase inhibitors | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| US-5120742-A | Androstanes as enzyme inhibitors | MERCK & CO., INC. (US) | 1992-06-09 | — | — | US | disclosed |
| US-5049562-A | Enzyme inhibitors, antiandrogens | MERCK & CO., INC. (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0414490-A2 | 17 Beta-acyl-4-aza-5 alpha-androst-1-ene-3-one as 5 alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0414491-A2 | 17 Beta-acyl-4-aza-5 alpha-androst-1-ene-3-ones as 5 alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4859681-A | 17 α-Acyl-4-aza-5a-androst-1-en-3-ones as 5 alpha-reductase inhibitors | MERCK & CO., INC. (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0271219-A1 | Topical pharmaceutical composition containing 17-beta-methoxycarbonyl-4-methyl-4-aza-5-alpha-androst-1-en-3-one | MERCK & CO. INC. (US) | 1988-06-15 | — | — | EP | disclosed |
| EP-0155096-A2 | 17 Beta-Substituted-4-aza-5-alpha-androstenones and their use as 5-alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1985-09-18 | — | — | EP | disclosed |