Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571159 | 0.90 | PTGS2 (0.36) | — | |
| SCHEMBL9571087 | 0.90 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL9571146 | 0.87 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL9571139 | 0.86 | CYP1A2 (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL9571126 | 0.85 | CYP1A2 (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL9571092 | 0.85 | CYP1A2 (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL8640917 | 0.82 | PKM (0.30) | — | |
| SCHEMBL9571162 | 0.81 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL9571088 | 0.80 | PTGS2 (0.35) | — | |
| SCHEMBL9571130 | 0.80 | PTGS2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552645-A2 | Process for the conversion of chlorinated aromatic compounds using electrophiles | MERCK PATENT GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |