Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640268 | 0.90 | PTGS2 (0.36) | — | |
| SCHEMBL8642159 | 0.90 | — | — | |
| SCHEMBL8642880 | 0.87 | — | — | |
| SCHEMBL8645125 | 0.86 | CYP1A2 (0.31) | — | |
| SCHEMBL8642971 | 0.85 | ALDH1A1 (0.33) | — | |
| SCHEMBL8641996 | 0.85 | ALDH1A1 (0.33) | — | |
| SCHEMBL9571122 | 0.82 | HTR2A (0.33) | — | |
| SCHEMBL8638646 | 0.80 | PTGS2 (0.38) | — | |
| SCHEMBL8642283 | 0.80 | PTGS2 (0.35) | — | |
| SCHEMBL8639954 | 0.80 | PTGS2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440082-B1 | Method for the conversion of fluorinated aromatic compounds using electrophiles | MERCK PATENT GMBH (DE) | 1998-04-15 | — | — | EP | disclosed |
| US-5262556-A | Alkylation or hydroxyalkylation by deprotonation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-11-16 | — | — | US | disclosed |
| EP-0440082-A2 | Method for the conversion of fluorinated aromatic compounds using electrophiles | MERCK PATENT GmbH (DE) | 1991-08-07 | — | — | EP | disclosed |