Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540215 | 0.86 | USP2 (0.38) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL9539805 | 0.80 | PGR (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9540102 | 0.71 | MEN1 (0.37) | ALDH1A1MAPTGAAKDM4ERAB9A | |
| SCHEMBL9539937 | 0.70 | CHRM1 (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9540047 | 0.68 | PGR (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9539803 | 0.68 | PGR (0.38) | ALDH1A1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL9539722 | 0.68 | AKR1B1 (0.50) | MAPTGAAPGRTSHRCYP2C19 | |
| SCHEMBL9540133 | 0.67 | PGR (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9539997 | 0.67 | PGR (0.39) | ALDH1A1MAPTALOX12SMN1; SMN2PGR | |
| SCHEMBL9540169 | 0.66 | IDO1 (0.41) | MEN1KMT2ATP53PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530994-A1 | Quinazoline derivatives as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1993-03-10 | — | — | EP | disclosed |