Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571985 | 1.00 | MAPT (0.42) | MAPTCYP2C9CES2CES1CYP1A2 | |
| SCHEMBL9571981 | 0.92 | MAPT (0.50) | MAPTCYP2C9CES2CES1CYP1A2 | |
| SCHEMBL9571976 | 0.92 | MAPT (0.50) | MAPTCYP2C9CES2CES1CYP1A2 | |
| SCHEMBL9978409 | 0.86 | KMT2A (0.48) | MAPTCES2CES1ALDH1A1KMT2A | |
| SCHEMBL13485707 | 0.84 | CYP1A2 (0.45) | MAPTCES2CES1CYP1A2POLB | |
| SCHEMBL787945 | 0.82 | CYP1A2 (0.48) | MAPTCES2CES1CYP1A2POLB | |
| SCHEMBL18647722 | 0.79 | — | — | |
| SCHEMBL28042801 | 0.78 | KMT2A (0.45) | MAPTCES2CES1ALDH1A1KMT2A | |
| SCHEMBL15759102 | 0.78 | GNAI3 (0.51) | MAPTCES2CES1POLBGNAI3 | |
| SCHEMBL8683446 | 0.78 | CYP1A2 (0.53) | MAPTCYP2C9CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |