Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562286 | 0.80 | CCR6 (0.62) | CCR6HKDC1PTPRCCDC25BBACE1 | |
| SCHEMBL9572020 | 0.74 | PTPRC (0.53) | PTPRCPRKCAGSK3B | |
| SCHEMBL8992318 | 0.72 | PTPRC (0.70) | CCR6HKDC1PTPRCCDC25BPTPRF | |
| SCHEMBL9561901 | 0.72 | CCR6 (0.56) | CCR6HKDC1PTPRCIMPDH2CAMK2D | |
| SCHEMBL9561922 | 0.70 | CCR6 (0.51) | CCR6HKDC1PTPRCIMPDH2CAMK2D | |
| SCHEMBL9571998 | 0.67 | PTPRC (0.51) | CCR6HKDC1PTPRCCDC25BBACE1 | |
| SCHEMBL9572012 | 0.66 | BACE1 (0.57) | CCR6HKDC1PTPRCCDC25BBACE1 | |
| SCHEMBL9562546 | 0.66 | BACE1 (0.57) | CCR6HKDC1PTPRCCDC25BBACE1 | |
| SCHEMBL9572001 | 0.66 | PTPRC (0.50) | CCR6HKDC1PTPRCCDC25BIMPDH2 | |
| SCHEMBL9572023 | 0.66 | MEN1 (0.51) | CCR6HKDC1PTPRCIMPDH2CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |