Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 9/20 | 0.44 |
| ▸ | CTSD | P07339 | 8/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17951617 | 0.83 | CTSD (0.49) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL21012039 | 0.82 | CTSD (0.50) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL20255738 | 0.82 | CTSD (0.50) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL16557153 | 0.82 | ALDH1A1 (0.54) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL8972235 | 0.81 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL21049238 | 0.81 | ALDH1A1 (0.60) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL17210508 | 0.81 | CTSD (0.52) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL21049237 | 0.81 | ALDH1A1 (0.60) | ALDH1A1BACE1CTSDFOLH1CTSB | |
| SCHEMBL28564205 | 0.81 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL17536608 | 0.81 | ALDH1A1 (0.60) | ALDH1A1BACE1CTSDFOLH1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543310-B1 | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5395824-A | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |