Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573321 | 0.84 | EPHX2 (0.50) | EPHX2MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL9572914 | 0.76 | KDM4E (0.50) | MAPTKMT2ALMNASMN1; SMN2GABRA1 | |
| SCHEMBL9572939 | 0.75 | ALOX15 (0.45) | MAPTLMNAKDM4EGAAHPGD | |
| SCHEMBL17335626 | 0.72 | EPHX2 (0.97) | EPHX2MAPTKMT2AMEN1HPGD | |
| SCHEMBL28664721 | 0.71 | EPHX2 (1.00) | EPHX2MAPTKMT2AMEN1HPGD | |
| SCHEMBL28721305 | 0.71 | EPHX2 (1.00) | EPHX2MAPTKMT2AMEN1HPGD | |
| SCHEMBL28721241 | 0.71 | EPHX2 (1.00) | EPHX2MAPTKMT2AMEN1HPGD | |
| SCHEMBL29549399 | 0.71 | EPHX2 (1.00) | EPHX2MAPTKMT2AMEN1HPGD | |
| SCHEMBL17778311 | 0.71 | EPHX2 (1.00) | EPHX2MAPTKMT2AMEN1HPGD | |
| SCHEMBL15417418 | 0.69 | EPHX2 (0.83) | EPHX2HPGDALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562832-A1 | Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |