Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573321 | 0.84 | EPHX2 (0.50) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL16254239 | 0.77 | ALDH1A1 (0.55) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL9572939 | 0.77 | ALOX15 (0.45) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL14602583 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL9572816 | 0.76 | EPHX2 (0.54) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL9268276 | 0.76 | OXER1 (0.62) | KDM4EALDH1A1HPGDHTTOXER1 | |
| SCHEMBL15512501 | 0.76 | OXER1 (0.62) | KDM4EALDH1A1HPGDHTTOXER1 | |
| SCHEMBL17022468 | 0.72 | OXER1 (0.62) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| Carbazole SCHEMBL28847016 | 0.72 | OXER1 (0.61) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL5728171 | 0.72 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562832-A1 | Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |