Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578872 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTGAAALDH1A1 | |
| SCHEMBL8435157 | 0.95 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMHTTGAAALDH1A1 | |
| SCHEMBL8436042 | 0.95 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMHTTGAAALDH1A1 | |
| SCHEMBL8579491 | 0.91 | GAA (0.42) | SMN1; SMN2GAAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8576659 | 0.91 | GAA (0.43) | SMN1; SMN2PKMHTTGAAALDH1A1 | |
| SCHEMBL9574300 | 0.91 | GAA (0.43) | SMN1; SMN2PKMHTTGAAALDH1A1 | |
| SCHEMBL8579494 | 0.90 | ALDH1A1 (0.38) | SMN1; SMN2GAAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8095064 | 0.90 | ALDH1A1 (0.43) | SMN1; SMN2GAAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8095066 | 0.90 | ALDH1A1 (0.43) | SMN1; SMN2GAAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8575147 | 0.89 | GAA (0.41) | SMN1; SMN2HTTGAAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |