Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095064 | 1.00 | ALDH1A1 (0.43) | ALDH1A1NPSR1TP53KDM4ELMNA | |
| SCHEMBL7458116 | 0.96 | ALDH1A1 (0.42) | ALDH1A1NPSR1TP53KDM4ELMNA | |
| SCHEMBL7458108 | 0.96 | ALDH1A1 (0.42) | ALDH1A1NPSR1TP53KDM4ELMNA | |
| SCHEMBL8094981 | 0.94 | ALDH1A1 (0.40) | ALDH1A1NPSR1TP53KDM4ELMNA | |
| SCHEMBL8578872 | 0.90 | SMN1; SMN2 (0.41) | ALDH1A1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL9574236 | 0.90 | SMN1; SMN2 (0.41) | ALDH1A1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL8438096 | 0.89 | ALDH1A1 (0.44) | ALDH1A1NPSR1TP53MAPTGAA | |
| SCHEMBL8438094 | 0.89 | ALDH1A1 (0.44) | ALDH1A1NPSR1TP53MAPTGAA | |
| SCHEMBL8435157 | 0.88 | SMN1; SMN2 (0.45) | ALDH1A1MAPTGAAMAPK1L3MBTL1 | |
| SCHEMBL8436042 | 0.88 | SMN1; SMN2 (0.45) | ALDH1A1MAPTGAAMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |