Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574263 | 0.88 | MAPT (0.40) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL8439013 | 0.84 | DPP8 (0.36) | DPP8DPP9ALDH1A1MAPTGAA | |
| SCHEMBL8435826 | 0.82 | EPHX2 (0.38) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL8435100 | 0.82 | ALDH1A1 (0.38) | DPP8DPP9ALDH1A1MAPTGAA | |
| SCHEMBL9574384 | 0.81 | ALDH1A1 (0.36) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL9574276 | 0.81 | ALDH1A1 (0.36) | DPP8DPP9ALDH1A1MAPTRAB9A | |
| SCHEMBL8435951 | 0.81 | SMN1; SMN2 (0.37) | DPP8DPP9ALDH1A1MAPTGAA | |
| SCHEMBL9877543 | 0.79 | RAB9A (0.44) | DPP8DPP9ALDH1A1MAPTGAA | |
| SCHEMBL9574308 | 0.78 | ATM (0.38) | DPP8DPP9ALDH1A1MAPTGAA | |
| SCHEMBL9724490 | 0.77 | RAB9A (0.41) | ALDH1A1MAPTRAB9AATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |