Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574298 | 0.87 | TDP1 (0.39) | TDP1TSHRSMN1; SMN2VCAM1CYP3A4 | |
| SCHEMBL10482176 | 0.79 | TDP1 (0.58) | TDP1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10654745 | 0.79 | KMT2A (0.49) | TDP1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9574404 | 0.73 | VCAM1 (0.47) | VCAM1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL1317710 | 0.73 | KMT2A (0.63) | TDP1MEN1KMT2AALDH1A1F2 | |
| SCHEMBL29508624 | 0.73 | KMT2A (0.63) | TDP1MEN1KMT2AALDH1A1F2 | |
| SCHEMBL11817089 | 0.72 | ALDH1A1 (0.52) | TDP1TSHRSMN1; SMN2VCAM1CYP3A4 | |
| SCHEMBL9719281 | 0.70 | TDP1 (0.71) | TDP1TSHRSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL30503599 | 0.70 | TDP1 (0.71) | TDP1TSHRSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL17747892 | 0.69 | TDP1 (0.48) | TDP1TSHRSMN1; SMN2VCAM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310944-B1 | BISOXETHYLSULFONYLMETHYL ANILINES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-13 | — | — | EP | claimed |
| EP-0310944-A2 | Bisoxethylsulfonylmethyl anilines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-12 | — | — | EP | claimed |
| EP-0310944-B1 | BISOXETHYLSULFONYLMETHYL ANILINES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-13 | — | — | EP | disclosed |
| EP-0310944-A2 | Bisoxethylsulfonylmethyl anilines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-12 | — | — | EP | disclosed |