Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | CUL4A | Q13619 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688433 | 0.80 | POLB (0.48) | KMT2AALDH1A1CUL4AKDM4EMAPT | |
| SCHEMBL2181967 | 0.73 | ALDH1A1 (0.57) | KMT2AALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL6972860 | 0.71 | HTT (0.40) | KMT2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2486696 | 0.69 | CUL4A (0.47) | KMT2AALDH1A1CUL4AKDM4EMAPT | |
| SCHEMBL10973674 | 0.68 | MMP1 (0.44) | KMT2AALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL6968831 | 0.67 | KMT2A (0.41) | KMT2AALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL363895 | 0.67 | ALDH1A1 (0.40) | KMT2AALDH1A1CUL4AMAPTNPC1 | |
| SCHEMBL6451238 | 0.67 | ALDH1A1 (0.55) | KMT2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2323034 | 0.66 | ALDH1A1 (0.50) | KMT2AALDH1A1CUL4ANPC1RAB9A | |
| SCHEMBL2484716 | 0.66 | CUL4A (0.41) | KMT2AALDH1A1CUL4AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563705-A2 | Cycloalkyl- and heterocyclyl substituted imidazolylpropenic acid derivatives | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |