SCHEMBL9575169

SCHEMBL9575169

C=CC(=O)Nc1cc(C)c(O)c(C)c1C

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 9/20 0.47
F13A1 P00488 1/20 0.40
LMNA P02545 1/20 0.40
TGM1 P22735 1/20 0.40
TGM3 Q08188 1/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
RORC P51449 2/20 0.38
SOAT2 O75908 1/20 0.38
ACAT1 P24752 1/20 0.38
SOAT1 P35610 1/20 0.38
BCL2A1 Q16548 1/20 0.36
BTK Q06187 3/20 0.36
PTPN1 P18031 1/20 0.36
PTPN11 Q06124 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27801542 0.78 TGM2 (0.58) TGM2F13A1LMNATGM1TGM3
SCHEMBL28550142 0.74 TGM2 (0.49) TGM2F13A1LMNATGM1TGM3
SCHEMBL10714648 0.74 GAA (0.59) TGM2F13A1LMNATGM1TGM3
SCHEMBL8079767 0.72 LMNA (0.49) LMNAMAOASOAT2ACAT1SOAT1
SCHEMBL11508898 0.72 TGM2 (0.61) TGM2F13A1LMNATGM1TGM3
SCHEMBL23293735 0.72 TGM2 (0.47) TGM2F13A1LMNATGM1TGM3
SCHEMBL18763028 0.72 TGM2 (0.43) TGM2F13A1LMNATGM1TGM3
SCHEMBL273479 0.72 TGM2 (0.43) TGM2F13A1LMNATGM1TGM3
SCHEMBL10956029 0.72 TGM2 (0.40) TGM2MAOAMAOBRORCBTK
SCHEMBL14279420 0.72 TGM2 (0.51) TGM2BCL2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0559892-A1 THERMOPLASTIC RESIN COMPOSITION AND PRODUCTION THEREOF KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-09-15 EP disclosed
EP-0559890-A1 THERMOPLASTIC RESIN COMPOSITION AND PRODUCTION THEREOF KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-09-15 EP disclosed
EP-0146130-B1 GLYCIDYL COMPOUND AND PROCESS FOR PREPARING THE SAME KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-10-26 EP disclosed
US-4709062-A Glycidyl compound KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-11-24 US disclosed
EP-0146130-A2 Glycidyl compound and process for preparing the same KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-06-26 EP disclosed