Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.41 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 3/20 | 0.38 |
| ▸ | SELL | P14151 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446353 | 0.76 | SOAT1 (0.53) | SOAT2ACAT1SOAT1THRBALDH1A1 | |
| SCHEMBL9446291 | 0.76 | SOAT1 (0.53) | SOAT2ACAT1SOAT1THRBALDH1A1 | |
| SCHEMBL9446297 | 0.76 | SOAT1 (0.53) | SOAT2ACAT1SOAT1THRBALDH1A1 | |
| SCHEMBL9446351 | 0.76 | SOAT1 (0.53) | SOAT2ACAT1SOAT1THRBALDH1A1 | |
| SCHEMBL9446388 | 0.76 | SOAT1 (0.53) | SOAT2ACAT1SOAT1THRBALDH1A1 | |
| SCHEMBL9446324 | 0.76 | SOAT1 (0.53) | SOAT2ACAT1SOAT1THRBALDH1A1 | |
| SCHEMBL9446369 | 0.76 | SOAT1 (0.53) | SOAT2ACAT1SOAT1THRBALDH1A1 | |
| SCHEMBL9446337 | 0.76 | SOAT1 (0.53) | SOAT2ACAT1SOAT1THRBALDH1A1 | |
| SCHEMBL9575169 | 0.72 | TGM2 (0.47) | LMNASOAT2ACAT1SOAT1MAOA | |
| SCHEMBL8644194 | 0.72 | ALDH1A1 (0.39) | LMNASOAT2ACAT1SOAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871611-B1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PF MEDICAMENT (FR) | 2000-09-13 | — | — | EP | disclosed |
| EP-0871611-A1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PIERRE FABRE MEDICAMENT (FR) | 1998-10-21 | — | — | EP | disclosed |
| US-5760087-A | ANTICHOLESTEROL AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1998-06-02 | — | — | US | disclosed |
| WO-1996022279-A1 | NEW DERIVATIVES OF GLYCYLANILIDES, PREPARATION AND THERAPEUTICAL APPLICATION | PIERRE FABRE MEDICAMENT (FR) | 1996-07-25 | — | — | WO | disclosed |