Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428042 | 0.88 | REN (0.36) | REN | |
| SCHEMBL9574983 | 0.87 | REN (0.46) | REN | |
| SCHEMBL7433348 | 0.78 | REN (0.54) | REN | |
| SCHEMBL7431811 | 0.74 | PSMB5 (0.41) | REN | |
| SCHEMBL7375834 | 0.72 | REN (0.47) | RENCTSS | |
| SCHEMBL7316049 | 0.72 | REN (0.42) | RENCTSLCTSBCTSS | |
| SCHEMBL7317681 | 0.72 | REN (0.42) | RENCTSLCTSBCTSS | |
| SCHEMBL7316055 | 0.72 | REN (0.42) | RENCTSLCTSBCTSS | |
| SCHEMBL9575060 | 0.70 | CTSS (0.33) | RENCTSLCTSBCTSS | |
| SCHEMBL7437072 | 0.70 | REN (0.35) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217958-A | Hypotensive agents | E. R. SQUIBB & SONS, INC. (US) | 1993-06-08 | — | — | US | disclosed |
| WO-1989007940-A1 | 1,2-HYDROXY PHOSPHONATES AND DERIVATIVES THEREOF | E.R. SQUIBB & SONS, INC. (US) | 1989-09-08 | — | — | WO | disclosed |