Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.69 |
| ▸ | METAP2 | P50579 | 9/20 | 0.46 |
| ▸ | METAP1 | P53582 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683843 | 1.00 | REN (0.69) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9575386 | 0.86 | REN (0.56) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9858518 | 0.86 | REN (0.56) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL9685661 | 0.86 | REN (0.56) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL4065186 | 0.86 | REN (0.55) | RENMETAP2METAP1ALDH1A1KMT2A | |
| SCHEMBL7367047 | 0.85 | REN (0.55) | RENMETAP2METAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7360375 | 0.84 | REN (0.54) | RENMETAP2METAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL27673691 | 0.84 | REN (0.54) | RENMETAP2METAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10676905 | 0.84 | REN (0.54) | RENMETAP2METAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9876283 | 0.84 | REN (0.54) | RENMETAP2METAP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504679-A1 | New imidazopyridines as serotonergic 5-HT3 antagonists | G.D. Searle & Co. (US) | 1992-09-23 | — | — | EP | disclosed |
| US-5091425-A | Inhibitors of the catalytic action of renin | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |