Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578905 | 0.82 | MMP8 (0.35) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL1828667 | 0.82 | MMP8 (0.35) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL31054671 | 0.82 | MMP8 (0.35) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL1578908 | 0.82 | MMP8 (0.35) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL27915963 | 0.79 | MMP8 (0.33) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL13573093 | 0.78 | MMP8 (0.33) | ALDH1A1LMNAHSD17B10HPGDMMP8 | |
| SCHEMBL13573094 | 0.78 | METAP2 (0.35) | ALDH1A1LMNAHSD17B10HPGDMMP8 | |
| SCHEMBL16786277 | 0.77 | CYP2D6 (0.33) | ALDH1A1CYP4F2CYP4A11ALOX15PKM | |
| SCHEMBL7595924 | 0.76 | GAA (0.39) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL839745 | 0.75 | CA2 (0.39) | POLBCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258183-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-4-HYDROXYVALERIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| US-5010189-A | Processes for the preparation of 5-amino-4-hydroxy-valeric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| US-4898977-A | Processes for the preparation of 5-amino-4-hydroxyvaleric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |