Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576707 | 0.82 | SMN1; SMN2 (0.47) | KDM4ESMN1; SMN2 | |
| SCHEMBL9575158 | 0.79 | TDP1 (0.33) | — | |
| SCHEMBL11425812 | 0.77 | FABP3 (0.42) | FABP3FABP4KDM4EEIF4A3SMN1; SMN2 | |
| SCHEMBL9575199 | 0.76 | MEN1 (0.41) | SMN1; SMN2 | |
| SCHEMBL11421086 | 0.75 | LMNA (0.43) | FABP3FABP4KDM4ESMN1; SMN2FABP5 | |
| SCHEMBL9575148 | 0.73 | CYP4F2 (0.41) | — | |
| SCHEMBL11610312 | 0.73 | FABP3 (0.39) | FABP3FABP4KDM4EEIF4A3SMN1; SMN2 | |
| SCHEMBL11475059 | 0.73 | MEN1 (0.47) | FABP3FABP4KDM4ESMN1; SMN2FABP5 | |
| SCHEMBL9575635 | 0.72 | TPMT (0.35) | — | |
| SCHEMBL16641111 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| EP-0249867-B1 | SUBSTITUTED PHENYL ESTERS OF ALPHA-FLUOROACRYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |