Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575440 | 0.79 | FABP3 (0.35) | — | |
| SCHEMBL9575199 | 0.77 | MEN1 (0.41) | TDP1THRB | |
| SCHEMBL9575371 | 0.73 | CHEK2 (0.37) | TDP1 | |
| SCHEMBL9576707 | 0.72 | SMN1; SMN2 (0.47) | THRB | |
| SCHEMBL9575148 | 0.71 | CYP4F2 (0.41) | — | |
| SCHEMBL9575341 | 0.70 | MRGPRX4 (0.42) | TDP1 | |
| SCHEMBL9575396 | 0.69 | LMNA (0.55) | — | |
| SCHEMBL9575635 | 0.69 | TPMT (0.35) | — | |
| SCHEMBL16641111 | 0.69 | — | — | |
| SCHEMBL9655860 | 0.68 | CYP3A4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| EP-0249867-B1 | SUBSTITUTED PHENYL ESTERS OF ALPHA-FLUOROACRYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |