Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021299 | 0.85 | ACHE (0.42) | ACHEBCHEADORA2AADORA1ADORA3 | |
| SCHEMBL9575539 | 0.83 | MEN1 (0.48) | ACHEMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL9845279 | 0.81 | MEN1 (0.39) | MEN1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL9021427 | 0.80 | ACHE (0.42) | ACHEBCHEADORA2AADORA1ADORA3 | |
| SCHEMBL9575361 | 0.80 | BCHE (0.48) | ACHEBCHEADORA2AADORA1ADORA3 | |
| SCHEMBL9021161 | 0.78 | BCHE (0.50) | ACHEBCHEADORA2AADORA1ADORA3 | |
| SCHEMBL9021599 | 0.77 | ACHE (0.41) | ACHEBCHE | |
| SCHEMBL9021602 | 0.76 | ACHE (0.40) | ACHEBCHEADORA2AADORA1ADORA3 | |
| SCHEMBL9022568 | 0.75 | ACHE (0.41) | ACHEBCHEHTT | |
| SCHEMBL9019742 | 0.74 | ACHE (0.33) | ACHEBCHEMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |