Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.31 |
| ▸ | TKT | P29401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845265 | 0.86 | TSHR (0.40) | MEN1KMT2ATSHRMAPK1HBB | |
| SCHEMBL9019807 | 0.85 | PDE3A (0.32) | MEN1KMT2AHTTSMN1; SMN2CCR4 | |
| SCHEMBL9019764 | 0.82 | PDE3A (0.38) | MEN1KMT2ASMN1; SMN2TKT | |
| SCHEMBL9019796 | 0.81 | CYP3A4 (0.41) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL9575496 | 0.81 | ACHE (0.42) | MEN1KMT2ATSHRMAPK1HBB | |
| SCHEMBL9845272 | 0.80 | CYP3A4 (0.35) | MEN1KMT2ATSHRSMN1; SMN2TKT | |
| SCHEMBL9845278 | 0.80 | SYK (0.31) | MEN1KMT2ATSHRCCR4 | |
| SCHEMBL9845246 | 0.79 | BCHE (0.36) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL9019826 | 0.78 | ALDH1A1 (0.37) | MEN1KMT2ATSHRSMN1; SMN2TKT | |
| SCHEMBL9019800 | 0.77 | BCHE (0.38) | MEN1KMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |