Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575718 | 0.88 | ALDH1A1 (0.39) | MAPTPOLBALDH1A1USP2CACNA1B | |
| SCHEMBL3975354 | 0.84 | THRA (0.38) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4456470 | 0.80 | ALDH1A1 (0.50) | MAPTPOLBALDH1A1USP2CACNA1B | |
| SCHEMBL788296 | 0.80 | SMN1; SMN2 (0.50) | MAPTPOLBALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL19644362 | 0.80 | SMN1; SMN2 (0.50) | MAPTPOLBALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL9614864 | 0.79 | SMN1; SMN2 (0.48) | MAPTALDH1A1SMN1; SMN2CYP2D6HPGD | |
| SCHEMBL9819123 | 0.79 | THRB (0.56) | MAPTPOLBALDH1A1KMT2A | |
| SCHEMBL6049329 | 0.78 | ALDH1A1 (0.46) | MAPTPOLBALDH1A1USP2CACNA1B | |
| SCHEMBL7948936 | 0.78 | CASR (0.39) | MAPTPOLBALDH1A1ADRB2ADRB1 | |
| SCHEMBL9174795 | 0.78 | THRB (0.56) | ALDH1A1SMN1; SMN2TP53GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281941-B1 | Coreactive photoinitiators | CIBA GEIGY AG (CH) | 1993-12-08 | — | — | EP | claimed |