Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27281765 | 0.83 | NLRP3 (0.45) | MEN1KMT2ANPC1TDP1HDAC6 | |
| SCHEMBL12818915 | 0.76 | MAOB (0.43) | MEN1KMT2ATDP1HDAC6KEAP1 | |
| SCHEMBL29879322 | 0.76 | MAOB (0.43) | MEN1KMT2ATDP1HDAC6KEAP1 | |
| SCHEMBL9575319 | 0.76 | LTB4R2 (0.46) | ADRA2CTDP1NPSR1OPRM1OPRD1 | |
| SCHEMBL3059779 | 0.75 | KMT2A (0.52) | MEN1KMT2ANPC1TDP1LPAR1 | |
| SCHEMBL698882 | 0.73 | ADRA2C (0.64) | MEN1KMT2ANPC1ADRA2CTDP1 | |
| SCHEMBL4773221 | 0.73 | TSHR (0.44) | MEN1KMT2ANPC1TDP1NPSR1 | |
| SCHEMBL4767667 | 0.71 | KMT2A (0.42) | MEN1KMT2ANPC1TDP1HDAC6 | |
| SCHEMBL11162092 | 0.70 | KDM4E (0.42) | MEN1KMT2ANPC1TDP1HDAC6 | |
| SCHEMBL10712041 | 0.69 | ALDH1A1 (0.40) | MEN1KMT2ANPC1TDP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280367-B1 | Glycine compounds | SHELL INT RESEARCH (NL) | 1993-11-03 | — | — | EP | disclosed |
| US-5110348-A | Pre-and postemergence | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1992-05-05 | — | — | US | disclosed |
| EP-0280367-A2 | Glycine compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-08-31 | — | — | EP | disclosed |