Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PRKCA | P17252 | 3/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575694 | 0.83 | EPHX1 (0.46) | EPHX1 | |
| SCHEMBL10831321 | 0.82 | EPHX1 (0.51) | LPAR3LPAR1EPHX1LPAR2 | |
| SCHEMBL10831323 | 0.80 | EPHX1 (0.50) | LPAR3LPAR1EPHX1 | |
| Hydrochloric Acid SCHEMBL9575957 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Hydrochloric Acid SCHEMBL9575952 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Hydrochloric Acid SCHEMBL9575947 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL7917187 | 0.80 | ALDH1A1 (0.84) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL896395 | 0.80 | ALDH1A1 (0.84) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL2733330 | 0.80 | ALDH1A1 (0.84) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL9575941 | 0.79 | KDM4E (0.57) | LMNALPAR3LPAR1ENPP2LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187293-A | Blood platelet activating factor inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-4731373-A | BLOOD PLATELET ACTIVATING FACTOR | HOFFMAN-LA ROCHE INC. (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0147768-A2 | Glycerin derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-07-10 | — | — | EP | disclosed |