Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 11/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575818 | 0.89 | ACHE (0.46) | ACHE | |
| SCHEMBL9575848 | 0.86 | LPAR6 (0.48) | ACHE | |
| SCHEMBL9575697 | 0.83 | ALDH1A1 (0.55) | EPHX1 | |
| SCHEMBL9575816 | 0.82 | LPAR5 (0.49) | ACHE | |
| SCHEMBL10831321 | 0.82 | EPHX1 (0.51) | EPHX1TLR2 | |
| SCHEMBL10831323 | 0.80 | EPHX1 (0.50) | EPHX1TLR2 | |
| SCHEMBL9671738 | 0.78 | PRKCA (0.50) | EPHX1ACHETLR2 | |
| SCHEMBL9575888 | 0.77 | EPHX1 (0.53) | EPHX1TLR2 | |
| SCHEMBL10832349 | 0.77 | EPHX1 (0.53) | EPHX1TLR2 | |
| SCHEMBL30866253 | 0.77 | EPHX1 (0.53) | EPHX1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187293-A | Blood platelet activating factor inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-4731373-A | BLOOD PLATELET ACTIVATING FACTOR | HOFFMAN-LA ROCHE INC. (US) | 1988-03-15 | — | — | US | disclosed |