SCHEMBL9575752

SCHEMBL9575752

CCC(=O)C(C)CC(C)C#N

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4928165 0.80 CES1 (0.38)
SCHEMBL11128512 0.78 TDP1 (0.37)
SCHEMBL19704836 0.78
SCHEMBL8613890 0.77 TSHR (0.36) TSHR
SCHEMBL8534653 0.77 NAALAD2 (0.43) TSHR
SCHEMBL12570564 0.74 RNPEP (0.39)
SCHEMBL19233793 0.72 SMN1; SMN2 (0.35) TSHR
SCHEMBL825523 0.72
SCHEMBL15092131 0.70 TSHR (0.37) TSHR
SCHEMBL24723772 0.70 ALDH1A1 (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0367598-B1 NOVEL PROCESS FOR THE PRODUCTION OF 4,6-DIMETHYL-7-HYDROXYNONAN-3-ONE Philip Morris Products Inc. (US) 1993-09-01 EP claimed
US-4925985-A GRIGNARD REACTION, REDUCTION, CATALYSIS PHILIP MORRIS INCORPORATED (US) 1990-05-15 US claimed
EP-0367598-A2 Novel process for the production of 4,6-dimethyl-7-hydroxynonan-3-one Philip Morris Products Inc. (US) 1990-05-09 EP claimed
JP-58021631-A None JP disclosed
JP-3161455-A None JP disclosed
EP-0367598-B1 NOVEL PROCESS FOR THE PRODUCTION OF 4,6-DIMETHYL-7-HYDROXYNONAN-3-ONE Philip Morris Products Inc. (US) 1993-09-01 EP disclosed
EP-0437290-A1 Process for the preparation of 5-oxohexane nitriles and the compound 2,4-dimethyl-5-oxohexane nitrile DSM N.V. (NL) 1991-07-17 EP disclosed
JP-H03161455-A NEW PROCESS FOR PRODUCTION OF 4,6-DIMETHYL-7-HYDROXYNONAN-3-ONE PHILIP MORRIS PROD INC 1991-07-11 JP disclosed
US-4925985-A GRIGNARD REACTION, REDUCTION, CATALYSIS PHILIP MORRIS INCORPORATED (US) 1990-05-15 US disclosed
EP-0367598-A2 Novel process for the production of 4,6-dimethyl-7-hydroxynonan-3-one Philip Morris Products Inc. (US) 1990-05-09 EP disclosed
JP-S5821631-A 4,6-DIMETHYL-NONANE DERIVATIVE AND SEX ATTARACTANT CONSISTING OF IT JAPAN TOBACCO INC 1983-02-08 JP disclosed